Preparation and Biocompatibility of Polyester Films Grafted with Functional mPEG Copolymers

doi:10.1007/s40242-017-7032-y

Chemical Research in Chinese Universities ›› 2017, Vol. 33 ›› Issue (5): 847-852.doi: 10.1007/s40242-017-7032-y

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Preparation and Biocompatibility of Polyester Films Grafted with Functional mPEG Copolymers

MA Yanhong¹, JIANG Yan^2,4, LIANG Yuan², ZHANG Weiwei³, ZHANG Hongwen², ZHANG Rong²

1. Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P. R. China;
2. College of Materials Science and Engineering, Changzhou University, Changzhou 213164, P. R. China;
3. College of Life Science, Agriculture and Forestry, Qiqihar University, Qiqihar 161006, P. R. China;
4. Jiangsu Chenguang Paint Co., Ltd., Changzhou 213154, P. R. China

Received:2017-01-18 Revised:2017-05-12 Online:2017-10-01 Published:2017-06-29
Contact: JIANG Yan,E-mail:yan_jiang@cczu.edu.cn E-mail:yan_jiang@cczu.edu.cn
Supported by:
Supported by the National Natural Science Foundation of China(No.51203015); the Natural Science Foundation of Jiangsu Province, China(No.BK2012786); Qing Lan Project and the Changzhou Science and Technology Support Program, China(No.CE20150002).

Abstract

Abstract:

The surface of poly(ethylene terephthalate)(PET) films is inert, hydrophobic, and incompatible with blood, which has limited its practical bioapplication. In this case, better biocompatibility could be achieved by surface modification. In this study, the grafted copolymer of functional methoxypolyethylene glycol(mPEG) derivatives and styrene from the PET surfaces was prepared via surface-initiated atom transfer radical polymerization(SI-ATRP). The structures, composition, properties and surface morphology of the grafted PET films were characterized by Fourier transform infrared spectroscopy(FTIR), X-ray photoelectron spectroscopy(XPS), contact angle measurements and scanning electronic microscopy(SEM). The results indicate that the surface of the PET films has been covered by a thick targeted copolymer layer that converted the hydrophobic surface of PET to an amphiphilic surface. The bacterial adhesion and cell culture results indicate the copolymer-grafted PET film may possess good biocompatibility.

Key words: Poly(ethylene terephthalate) film, Surface-initiated atom transfer radical polymerization(SI-ATRP), Biocompatibility

MA Yanhong, JIANG Yan, LIANG Yuan, ZHANG Weiwei, ZHANG Hongwen, ZHANG Rong. Preparation and Biocompatibility of Polyester Films Grafted with Functional mPEG Copolymers[J]. Chemical Research in Chinese Universities, 2017, 33(5): 847-852.

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Preparation and Biocompatibility of Polyester Films Grafted with Functional mPEG Copolymers

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