Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH

doi:10.1007/s40242-017-7218-3

高等学校化学研究 ›› 2018, Vol. 34 ›› Issue (1): 132-137.doi: 10.1007/s40242-017-7218-3

Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH

SUN Rui², WANG Ying¹, GOU Pengfei², ZUO Min², LI Xiaodong¹, ZHU Weipu², SHEN Zhiquan²

1. Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, P. R. China;
2. Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P. R. China

收稿日期:2017-06-23 出版日期:2018-02-01 发布日期:2018-01-20
通讯作者: WANG Ying,E-mail:306174@zju.edu.cn;ZHU Weipu,E-mail:zhuwp@zju.edu.cn E-mail:306174@zju.edu.cn;zhuwp@zju.edu.cn
基金资助:
Supported by the Distinguished Young Investigator Fund of Zhejiang Province, China(No.LR18B040001), the National Natural Science Foundation of China(No.51603180), the Fundamental Research Funds for the Central Universities, China (No.2017QNA4038) and the China Postdoctoral Science Foundation(No.2015M580517).

Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH

SUN Rui², WANG Ying¹, GOU Pengfei², ZUO Min², LI Xiaodong¹, ZHU Weipu², SHEN Zhiquan²

1. Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, P. R. China;
2. Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, P. R. China

Received:2017-06-23 Online:2018-02-01 Published:2018-01-20
Contact: WANG Ying,E-mail:306174@zju.edu.cn;ZHU Weipu,E-mail:zhuwp@zju.edu.cn E-mail:306174@zju.edu.cn;zhuwp@zju.edu.cn
Supported by:
Supported by the Distinguished Young Investigator Fund of Zhejiang Province, China(No.LR18B040001), the National Natural Science Foundation of China(No.51603180), the Fundamental Research Funds for the Central Universities, China (No.2017QNA4038) and the China Postdoctoral Science Foundation(No.2015M580517).

摘要/Abstract

摘要： Well-defined amphiphilic seven-arm star triblock copolymers containing hydrophobic crystalline poly(ε-caprolactone)(PCL) blocks, hydrophobic non-crystalline poly(tert-butyl acrylate)(PtBA) blocks and hydrophilic poly(ethylene glycol)(PEG) blocks were precisely synthesized by a combination of ring-opening polymerization(ROP), atom transfer radical polymerization(ATRP) and “click” reaction. Such star copolymers could self-assemble into “core-shell-corona” micelles and “multi-layer” vesicles depending on the fraction of each block. Meanwhile, the selective hydrolysis of middle PtBA blocks into the poly(acrylic acid)(PAA) blocks allowed the star block copolymers to further change their morphologies of aqueous aggregates in response to pH values.

关键词: Amphiphile, Crystallization, Hydrolysis, Self-assembly, Star block copolymer

Abstract: Well-defined amphiphilic seven-arm star triblock copolymers containing hydrophobic crystalline poly(ε-caprolactone)(PCL) blocks, hydrophobic non-crystalline poly(tert-butyl acrylate)(PtBA) blocks and hydrophilic poly(ethylene glycol)(PEG) blocks were precisely synthesized by a combination of ring-opening polymerization(ROP), atom transfer radical polymerization(ATRP) and “click” reaction. Such star copolymers could self-assemble into “core-shell-corona” micelles and “multi-layer” vesicles depending on the fraction of each block. Meanwhile, the selective hydrolysis of middle PtBA blocks into the poly(acrylic acid)(PAA) blocks allowed the star block copolymers to further change their morphologies of aqueous aggregates in response to pH values.

Key words: Amphiphile, Crystallization, Hydrolysis, Self-assembly, Star block copolymer

SUN Rui, WANG Ying, GOU Pengfei, ZUO Min, LI Xiaodong, ZHU Weipu, SHEN Zhiquan. Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH[J]. 高等学校化学研究, 2018, 34(1): 132-137.

参考文献

[1] Hadjichristidis N., Pitsikalis M., Pispas S., Iatrou H., Chem. Rew., 2001, 101(12), 3747
[2] Tezuka Y., Oike H., Prog. Polum. Sci., 2002, 27(6), 1069
[3] Ren J. M., Mckenzie T. G., Fu Q., Wong E. H. H., Xu J., An Z., Shanmugam S., Davis T. P., Boyer C., Qiao G. G., Chem. Rew., 2016, 116(12), 6743
[4] Zhou F., Zhou Q. H., Tian H. J., Li C. S., Zhang Y. D., Fan X. H., Shen Z. H., Chinese J. Polym. Sci., 2015, 33(5), 709
[5] Moughton A. O., Sagawa T., Yin L., Lodge T. P., Hillmyer M. A., ACS Omega, 2016, 1(5), 1027
[6] Liu T., Zhang Y. F., Liu S. Y., Chinese J. Polym. Sci., 2013, 31(6), 924
[7] Zhou Y., Huang W., Liu J., Zhu X., Yan D., Adv. Mater., 2010, 22(41), 4567
[8] Washington K. E., Kularatne R. N., Du J., Gillings M. J., Webb J. C., Doan N. C., Biewer M. C., Stefan M. C., J. Polym. Sci., Part A: Polym. Chem., 2016, 54(22), 3601
[9] Calderon M., Quadir M. A., Sharma S. K., Haag R., Adv. Mater., 2010, 22(2), 190
[10] Lin W., Hanson S., Han W., Zhang X., Yao N., Li H., Zhang L., Wang C., Acta. Biomater., 2017, 48, 378
[11] Chen G., Wang L., Cordie T., Vokoun C., Eliceiri K. W., Gong S., Biomaterials, 2015, 47, 41
[12] Xu Z., Liu S., Liu H., Yang C., Kang Y., Wang M., Chem. Commun., 2015, 51(87), 15768
[13] Zeng H. L., Gao C., Yan D. Y., Adv. Funct. Mater., 2006, 16(6), 812
[14] Zhu W., Wang Y., Sun S., Zhang Q., Li X., Shen Z., J. Mater. Chem., 2012, 22(23), 11785
[15] Veronese F. M., Biomaterials, 2001, 22(5), 405
[16] Zarafshani Z., Obata T., Lutz J. F., Biomacromolecules, 2010, 11(8), 2130
[17] Jiang Y., Li Y., Wang X., Shi Z., Cui Z., Chem. Res. Chinese Universities, 2017, 33(1), 150
[18] Wei X. W., Gong C. Y., Gou M. Y., Fu S. Z., Guo Q. F., Shi S., Luo F., Guo G., Qiu L. Y., Qian Z. Y., Int. J. Pharm., 2009, 381(1), 1
[19] Gou P. F., Zhu W. P., Xu N., Shen Z. Q., J. Polym. Sci., Part A: Polym. Chem., 2009, 47(24), 6962
[20] Gou P. F., Zhu W. P., Shen Z. Q., J. Polym. Sci., Part A: Polym. Chem., 2010, 48(24), 5643
[21] Zhu W. P., Gou P. F., Shen Z. Q., Prog. Chem., 2008, 20(5), 720
[22] Gao C., Wang Y., Zhu W. P., Shen Z. Q., Chinese J. Polym. Sci., 2014, 32(11), 1431
[23] Gao C., Wang Y., Gou P. F., Cai X., Li X. D., Zhu W. P., Shen Z. Q., J. Polym. Sci., Part A: Polym. Chem., 2013, 51(13), 2824
[24] Zhang Z. X., Liu X., Xu F. J., Loh X. J., Kang E. T., Neoh K. G., Li J., Macromolecules, 2008, 41(16), 5967
[25] Gou P. F., Zhu W. P., Shen Z. Q., Polym. Chem., 2010, 1(8), 1205
[26] Gou P. F., Zhu W. P., Xu N., Shen Z. Q., J. Polym. Sci., Part A: Polym. Chem., 2008, 46(19), 6455
[27] Bao H., Li L., Gan L. H., Ping Y., Li J., Ravi P., Macromolecules, 2010, 43(13), 5679
[28] Zhao X., Liu P., ACS Appl. Mater. Interfaces, 2015, 7(1), 166

Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH

Amphiphilic Seven-arm Star Triblock Copolymers with Diverse Morphologies in Aqueous Solution Induced by Crystallization and pH

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	GAO Huimin, SHI Rui, ZHU Youliang, QIAN Hujun and LU Zhongyuan. Coarse-grained Dynamics Simulation in Polymer Systems: from Structures to Material Properties[J]. 高等学校化学研究, 2022, 38(3): 653-670.
[2]	YANG Miao, WANG Wenjing, SU Kongzhao, YUAN Daqiang. Dimeric Calix[4]resorcinarene-based Porous Organic Cages for CO₂/CH₄ Separation[J]. 高等学校化学研究, 2022, 38(2): 428-432.
[3]	ZHANG Xiaosi, YANG Miao, TIAN Peng, LIU Zhongmin. Progress in Seed-assisted Synthesis of (Silico) Aluminophosphate Molecular Sieves[J]. 高等学校化学研究, 2022, 38(1): 1-8.
[4]	QIAO Junyi, LIU Xinyao, ZHANG Lirong, LIU Yunling. Self-assembly of 3p-Block Metal-based Metal-Organic Frameworks from Structural Perspective[J]. 高等学校化学研究, 2022, 38(1): 31-44.
[5]	FENG Enduo, TIAN Yang. Surface-enhanced Raman Scattering of Self-assembled Superstructures[J]. 高等学校化学研究, 2021, 37(5): 989-1007.
[6]	Andy Shun-Hoi CHEUNG, Sammual Yu-Lut LEUNG, Franky Ka-Wah HAU, Vivian Wing-Wah YAM. Supramolecular Self-assembly of Amphiphilic Alkynyl-platinum(II) 2,6-Bis(N-alkylbenzimidazol-2'-yl) pyridine Complexes[J]. 高等学校化学研究, 2021, 37(5): 1079-1084.
[7]	HAN Lin, WANG Yuang, TANG Wantao, LIU Jianbing, DING Baoquan. Bioimaging Based on Nucleic Acid Nanostructures[J]. 高等学校化学研究, 2021, 37(4): 823-828.
[8]	REN Yiqing, LIU Xinlong, GE Huan, GUO Yuanyuan, ZHANG Qiushuang, XIE Miao, WANG Ping, ZHU Xinyuan, ZHANG Chuan. A Combinatorial Approach Based on Nucleic Acid Assembly and Electrostatic Compression for siRNA Delivery[J]. 高等学校化学研究, 2021, 37(4): 906-913.
[9]	YANG Jia, ZHENG Rui, AN Hongwei, WANG Hao. In vivo Self-assembled Peptide Nanoprobes for Disease Diagnosis[J]. 高等学校化学研究, 2021, 37(4): 855-869.
[10]	LIU Zhiyu, LIANG Gaolin, ZHAN Wenjun. In situ Activatable Peptide-based Nanoprobes for Tumor Imaging[J]. 高等学校化学研究, 2021, 37(4): 889-899.
[11]	YANG Liming, GUO Lixin, YU Hao, WANG Guan, SUN Jiangman, ZHANG Pengfei, GU Xinggui, TANG Ben Zhong. Organic Nanocrystals Based on a Solid-emission-tunable AIEgen for Cell Imaging[J]. 高等学校化学研究, 2021, 37(1): 129-136.
[12]	LI Lun, XUE Xiaoxia, SUN Yimeng, ZHAO Wuduo, LI Tiesheng, LIU Minghua, WU Yangjie. Self-assembly Palladacycle Thiophene Imine Monolayer—Investigating on Catalytic Activity and Mechanism for Coupling Reaction[J]. 高等学校化学研究, 2020, 36(5): 821-828.
[13]	ZHANG Junjie, WANG Can, DUAN Ruomeng, PENG Chencheng, YANG Biao, CAO Nan, ZHANG Haiming, CHI Lifeng. Two-dimensional Molecular Phase Transition of Alkylated-TDPB on Au(111) and Cu(111) Surfaces[J]. 高等学校化学研究, 2020, 36(4): 685-689.
[14]	LIU Shengtang, YANG Miao, LIU Cheng, TIAN Bailin, DING Mengning. Superlattice Structure from Re-stacked NiFe Layer Double Hydroxides for Oxygen Evolution Reaction[J]. 高等学校化学研究, 2020, 36(4): 680-684.
[15]	PAN Gaifang, MA Yuan, ZHANG Jiao, GUO Yuanyuan, DING Fei, GE Huan, LI Qifeng, ZHU Xinyuan, ZHANG Chuan. Engineering a Floxuridine-integrated RNA Prism as Precise Nanomedicine for Drug Delivery[J]. 高等学校化学研究, 2020, 36(2): 274-280.