CRCU

Chemical Research in Chinese Universities ›› 2012, Vol. 28 ›› Issue (3): 542-545.

• Articles • Previous Articles     Next Articles

Surface Heparinization of Poly(ether ether ketone)

SUN Hui, CHEN Rui-chao, LIU Shu, XU Guo-zhi   

  1. Department of Materials and Mechanical Engineering, Beijing Technology and Business University, Beijing 100048, P. R. China
  • Received:2011-07-16 Revised:2011-09-10 Online:2012-05-25 Published:2012-05-03
  • Contact: SUN Hui E-mail:sunhui@th.btbu.edu.cn
  • Supported by:

    Supported by the Scientific and Technological Development Programs of Beijing Municipal Education Commission, China (No.KM201010011004), the Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education, China, the 2011 Merit-based Research Funding for Picked Returned Overseas Scholars, Beijing Municipality, China and Beijing Technology and Business University(China) Through a Research Project Approved for Graduates(No.19000101026

PDF (PC)

Cited

9

Abstract: Photo-grafting of hydrophilic monomer and space arms was used to enhance the hydrophilicity of poly(ether ether ketone)(PEEK) with the aim of extending its application to biological fields. PEEK films were surface modified by UV grafting of acrylic acid(AA) to introduce ―COOH on PEEK surface. Adipic amine was used as a space arm to introduce heparin on PEEK surface based on the condensation reaction between ―NH2 and ―COOH. The modified PEEK(PEEK-COOH, PEEK-NH2 and PEEK-Hep) was characterized by energy-disperse spectroscopy (EDS), X-ray photoelectron spectroscopy(XPS) and water contact angle measurements, which show that heparin was grafted on PEEK surface. The contact angles of modified PEEK films were lower than those of original films, demonstrating a significant improvement of surface hydrophilicity.

Key words: Poly(ether ether ketone)(PEEK), UV-Grafting, Space arm, Heparin immobilization