Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate

高等学校化学研究 ›› 2005, Vol. 21 ›› Issue (6): 673-676.

Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate

XU Liang-zhong, ZHU Chong-yi, YU Chen-long, LI Kai, SI Guo-dong

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China

收稿日期:2004-09-29 出版日期:2005-11-23 发布日期:2011-08-06

Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate

XU Liang-zhong, ZHU Chong-yi, YU Chen-long, LI Kai, SI Guo-dong

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China

Received:2004-09-29 Online:2005-11-23 Published:2011-08-06

摘要/Abstract

摘要： The title compound, 2-(4-fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate,was synthesized and its structure was confirmed by means of IR, MS, ¹H NMR and elemental analysis.The single crystal structure of the title compound was determined by X-ray diffraction.The preliminary biological test showed that the synthesized compound possesses some biological activities.

关键词: 1H-1,2,4-Triazole, Morpholine, Crystal structure, Biological activity

Abstract: The title compound, 2-(4-fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate,was synthesized and its structure was confirmed by means of IR, MS, ¹H NMR and elemental analysis.The single crystal structure of the title compound was determined by X-ray diffraction.The preliminary biological test showed that the synthesized compound possesses some biological activities.

Key words: 1H-1,2,4-Triazole, Morpholine, Crystal structure, Biological activity

XU Liang-zhong, ZHU Chong-yi, YU Chen-long, LI Kai, SI Guo-dong. Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate[J]. 高等学校化学研究, 2005, 21(6): 673-676.

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Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate

Synthesis, Crystal Structure and Biological Activities of 2-(4-Fluorophenyl)-2-oxo-1-(1H-1, 2,4-triazol-1-yl) ethyl morpholine-4-carbodithioate

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