Studies on Interaction Between Gallocyanine and DNA

高等学校化学研究 ›› 2002, Vol. 18 ›› Issue (3): 267-269.

Studies on Interaction Between Gallocyanine and DNA

ZHANG Gui-zhu¹, LU Ji-xin², WANG Yue-mei¹, HE Xi-wen¹

1. Department of Chemistry, Nankai University, Tianjin 300071, P. R. China;
2. Department of Pharmacy, Tianjin Medical University, Tianjin 300203, P. R. China.

收稿日期:2001-03-07 出版日期:2002-08-24 发布日期:2011-08-04
基金资助:
Supported by the National Natural Science Foundation of China.

Studies on Interaction Between Gallocyanine and DNA

ZHANG Gui-zhu¹, LU Ji-xin², WANG Yue-mei¹, HE Xi-wen¹

1. Department of Chemistry, Nankai University, Tianjin 300071, P. R. China;
2. Department of Pharmacy, Tianjin Medical University, Tianjin 300203, P. R. China.

Received:2001-03-07 Online:2002-08-24 Published:2011-08-04
Supported by:
Supported by the National Natural Science Foundation of China.

摘要/Abstract

摘要： The interaction of Gallocyanine(Gal) with DNA was studied by using UV spectra and circular dichroism(CD) spectrum methods. Gal and DNA strongly interacted on each other in acid solutions. The intrinsic binding constant(K) and the binding numbers(C_DNA/C_gal) of Gal and DNA are 2.25×10⁴ mol^-1 and 2.5, respectively. The influence of pH on the interaction of Gal and DNA was also studied.

关键词: Gallocyanine, DNA, UV-spectrum, CD-spectrum

Abstract: The interaction of Gallocyanine(Gal) with DNA was studied by using UV spectra and circular dichroism(CD) spectrum methods. Gal and DNA strongly interacted on each other in acid solutions. The intrinsic binding constant(K) and the binding numbers(C_DNA/C_gal) of Gal and DNA are 2.25×10⁴ mol^-1 and 2.5, respectively. The influence of pH on the interaction of Gal and DNA was also studied.

Key words: Gallocyanine, DNA, UV-spectrum, CD-spectrum

ZHANG Gui-zhu, LU Ji-xin, WANG Yue-mei, HE Xi-wen. Studies on Interaction Between Gallocyanine and DNA[J]. 高等学校化学研究, 2002, 18(3): 267-269.

ZHANG Gui-zhu, LU Ji-xin, WANG Yue-mei, HE Xi-wen. Studies on Interaction Between Gallocyanine and DNA[J]. Chemical Research in Chinese Universities, 2002, 18(3): 267-269.

[1]	ZHANG Qian, LIANG Yuyan, XING Hang. Caging-Decaging Strategies to Realize Spatiotemporal Control of DNAzyme Activity for Biosensing and Bioimaging[J]. 高等学校化学研究, 2022, 38(4): 902-911.
[2]	HUANG Qin, LIU Xin, ZHANG Pengge, WU Zhan, ZHAO Zilong. A DNA Nano-train Carrying a Predefined Drug Combination for Cancer Therapy[J]. 高等学校化学研究, 2022, 38(4): 928-934.
[3]	HAN Lin, WANG Yuang, TANG Wantao, LIU Jianbing, DING Baoquan. Bioimaging Based on Nucleic Acid Nanostructures[J]. 高等学校化学研究, 2021, 37(4): 823-828.
[4]	YIN Fangfei, CAO Nan, XIANG Xuelin, FENG Hao, LI Fan, LI Min, XIA Qiang, ZUO Xiaolei. DNA Framework-based Topological Aptamer for Differentiating Subtypes of Hepatocellular Carcinoma Cells[J]. 高等学校化学研究, 2021, 37(4): 919-924.
[5]	LIU Zhenyu, DONG Jinyi, PAN Jiahao, ZHOU Chao, FAN Chunhai, WANG Qiangbin. Catalytic DNA Origami-based Chiral Plasmonic Biosensor[J]. 高等学校化学研究, 2021, 37(4): 914-918.
[6]	HAO Xueyu, LI Chunjie, WANG Yu, ZHANG Feng, HOU Jingwei, KANG Chunqing, GAO Lianxun. NDI-induced Topological Conversion of Human Telomeric G-Quadruplexes from Hybrid-2 to Parallel Form[J]. 高等学校化学研究, 2021, 37(3): 795-800.
[7]	HU Qinyu, WU Jun, CHEN Lulu, LOU Xiaoding, XIA Fan. Recent Development of DNA-modified AIEgen Probes for Biomedical Application[J]. 高等学校化学研究, 2021, 37(1): 66-72.
[8]	LIU Shuo, YANG Mingjie, GUO Weiwei. Programmable and Reversible Regulation of Catalytic Hemin@MOFs Activities with DNA Structures[J]. 高等学校化学研究, 2020, 36(2): 301-306.
[9]	ZHU Jinjin, SHANG Yingxu, YU Haiyin, LI Na, DING Baoquan. Shape-controllable Synthesis of Functional Nanomaterials on DNA Templates[J]. 高等学校化学研究, 2020, 36(2): 171-176.
[10]	LI Tao, DUAN Ruilin, DUAN Zhijuan, HUANG Fujian, XIA Fan. Fluorescence Signal Amplification Strategies Based on DNA Nanotechnology for miRNA Detection[J]. 高等学校化学研究, 2020, 36(2): 194-202.
[11]	YANG Linlin, MIAO Yanyan, HAN Da. DNA Nanotechnology on Live Cell Membranes[J]. 高等学校化学研究, 2020, 36(2): 203-210.
[12]	WANG Mingyang, DUAN Jialin, DAI Lizhi, XIN Xiaodong, WANG Fangfang, LI Zheng, TIAN Ye. Characterization of 3D DNA Assemblies Using Cryogenic Electron Microscopy[J]. 高等学校化学研究, 2020, 36(2): 227-236.
[13]	DONG Yuhang, PAN Xiaorui, LI Feng, YANG Dayong. pH-Responsive Reversible DNA Self-assembly Mediated by Zwitterion[J]. 高等学校化学研究, 2020, 36(2): 285-290.
[14]	CAO Mengyao, SUN Yueyang, XIAO Mingshu, LI Li, LIU Xiaohui, JIN Hong, PEI Hao. Multivalent Aptamer-modified DNA Origami as Drug Delivery System for Targeted Cancer Therapy[J]. 高等学校化学研究, 2020, 36(2): 254-260.
[15]	LI Yujie, CHEN Jie, DONG Yuanchen, LIU Huajie, LIU Dongsheng. Construction of pH-Triggered DNA Hydrogels Based on Hybridization Chain Reactions[J]. 高等学校化学研究, 2020, 36(2): 243-246.

Studies on Interaction Between Gallocyanine and DNA

Studies on Interaction Between Gallocyanine and DNA

PDF (PC)

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价