New Chemical Compound from Caragana jubata (pall.) Poir.

高等学校化学研究 ›› 2010, Vol. 26 ›› Issue (4): 563-566.

New Chemical Compound from Caragana jubata (pall.) Poir.

SONG Ping^1*, YANG Xin-zhou² and YU Jun¹

1. Department of Chemistry, Qinghai University for Nationalities, Xining 810007, P. R. China;
2. Department of Pharmaceutical Sciences, University of Basel, Basel CH-4056, Switzerland

收稿日期:2009-09-21 修回日期:2009-10-17 出版日期:2010-07-25 发布日期:2010-10-01
通讯作者: SONG Ping. E-mail: spfenxi@126.com
基金资助:
Supported by the National Natural Science Foundation of China(No.30660221) and the Natural Science Foundation of Qinghai Province, China(No.2006-N-554).

New Chemical Compound from Caragana jubata (pall.) Poir.

SONG Ping^1*, YANG Xin-zhou² and YU Jun¹

1. Department of Chemistry, Qinghai University for Nationalities, Xining 810007, P. R. China;
2. Department of Pharmaceutical Sciences, University of Basel, Basel CH-4056, Switzerland

Received:2009-09-21 Revised:2009-10-17 Online:2010-07-25 Published:2010-10-01
Contact: SONG Ping. E-mail: spfenxi@126.com
Supported by:
Supported by the National Natural Science Foundation of China(No.30660221) and the Natural Science Foundation of Qinghai Province, China(No.2006-N-554).

摘要/Abstract

摘要： A new pterocarpan glycoside, (–)-maackiain 3-O-6'-O-acrylyl-β-D-galactopyranoside(1) was isolated from the whole parts of Caragana jubata(pall.) Poir., together with three known pterocarpan glycosides, (–)-maackiain 3-O-6'-O-acetyl-β-D-glucopyranoside(2), (–)-maackiain 3-O-β-D-glucopyranoside(3) and (–)-maackiain 3-O-β-D-galactopyranoside(4). All the compounds were isolated from the title plant for the first time. The structure of the new compound was established on the basis of detailed 1D, 2D NMR and circular dichroism spectroscopic analyses. All the compounds were evaluated for their cytotoxic activities against three tumor cell lines, A549, HL-60 and P388.

关键词: Caragana jubata(pall.) Poir., Flavonoid, Pterocarpan glycoside, Cytotoxicity

Abstract: A new pterocarpan glycoside, (–)-maackiain 3-O-6'-O-acrylyl-β-D-galactopyranoside(1) was isolated from the whole parts of Caragana jubata(pall.) Poir., together with three known pterocarpan glycosides, (–)-maackiain 3-O-6'-O-acetyl-β-D-glucopyranoside(2), (–)-maackiain 3-O-β-D-glucopyranoside(3) and (–)-maackiain 3-O-β-D-galactopyranoside(4). All the compounds were isolated from the title plant for the first time. The structure of the new compound was established on the basis of detailed 1D, 2D NMR and circular dichroism spectroscopic analyses. All the compounds were evaluated for their cytotoxic activities against three tumor cell lines, A549, HL-60 and P388.

Key words: Caragana jubata(pall.) Poir., Flavonoid, Pterocarpan glycoside, Cytotoxicity

SONG Ping*, YANG Xin-zhou and YU Jun. New Chemical Compound from Caragana jubata (pall.) Poir.[J]. 高等学校化学研究, 2010, 26(4): 563-566.

SONG Ping*, YANG Xin-zhou and YU Jun. New Chemical Compound from Caragana jubata (pall.) Poir.[J]. Chemical Research in Chinese Universities, 2010, 26(4): 563-566.

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New Chemical Compound from Caragana jubata (pall.) Poir.

New Chemical Compound from Caragana jubata (pall.) Poir.

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