Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety

高等学校化学研究 ›› 2010, Vol. 26 ›› Issue (3): 389-393.

Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety

PAN Li¹, LIU Xing-hai¹, SHI Yan-xia², WANG Bao-lei¹, WANG Su-hua¹, LI Bao-ju^2* and LI Zheng-ming^1*

1. State Key Laboratory of Elemento-Organic Chemistry, National Pesticidal Engineering Centre(Tianjin), Tianjin Key Laboratory of Pesticide Science, Nankai University, Tianjin 300071, P. R. China;
2. Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China

收稿日期:2009-05-19 修回日期:2009-06-28 出版日期:2010-05-25 发布日期:2010-07-27
通讯作者: LI Bao-ju. E-mail: nkzml@vip.163.com; LI Zheng-ming. E-mail: libj@mail.coas.net.cn
基金资助:
Supported by the National Basic Research Program of China(No.2010B12606).

Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety

PAN Li¹, LIU Xing-hai¹, SHI Yan-xia², WANG Bao-lei¹, WANG Su-hua¹, LI Bao-ju^2* and LI Zheng-ming^1*

1. State Key Laboratory of Elemento-Organic Chemistry, National Pesticidal Engineering Centre(Tianjin), Tianjin Key Laboratory of Pesticide Science, Nankai University, Tianjin 300071, P. R. China;
2. Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China

Received:2009-05-19 Revised:2009-06-28 Online:2010-05-25 Published:2010-07-27
Contact: LI Bao-ju. E-mail: nkzml@vip.163.com; LI Zheng-ming. E-mail: libj@mail.coas.net.cn
Supported by:
Supported by the National Basic Research Program of China(No.2010B12606).

摘要/Abstract

摘要：

Nine new α-aminophosphonate derivatives containing cyclopropane moiety have been synthesized via conventional and microwave irradiation methods under solvent- and catalyst-free condition. The structures of the title compounds have been confirmed by ¹H NMR, ³¹P NMR, FTIR, EI-MS and FTICR-MS. Their antifungal activities were evaluated in vivo and some of the compounds were found to exhibit excellent antifungal activities against Corynespora cassiicola, Pseudomonas syringae pv. Lachrymans, Pseudoperonospora cubensis and Sclerotinia sclerotiorum.

关键词: α-Aminophosphonate; Imine; Antifungal activity

Abstract:

Key words: α-Aminophosphonate; Imine; Antifungal activity

PAN Li, LIU Xing-hai, SHI Yan-xia, WANG Bao-lei, WANG Su-hua, LI Bao-ju*, .... Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety[J]. 高等学校化学研究, 2010, 26(3): 389-393.

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Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety

Solvent- and Catalyst-free Synthesis and Antifungal Activities of α-Aminophosphonate Containing Cyclopropane Moiety

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