Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel

doi:10.1007/s40242-024-4029-1

高等学校化学研究 ›› 2024, Vol. 40 ›› Issue (2): 326-332.doi: 10.1007/s40242-024-4029-1

Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel

LIU Huan, SUN Xueting, DAI Yu, ZHANG Xiaojin, XIA Fan

Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, P. R. China

收稿日期:2024-01-31 修回日期:2024-03-01 出版日期:2024-04-01 发布日期:2024-03-27
通讯作者: ZHANG Xiaojin zhangxj@cug.edu.cn;XIA Fan xiafan@cug.edu.cn
基金资助:
This work was supported by the National Natural Science Foundation of China (No. 22090050), the National Key R&D Program of China (No. 2021YFA1200403) and the Joint National Natural Science Foundation of China-Israel Science Foundation (NSFC-ISF) Research Grant Program (No. 22161142020).

Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel

LIU Huan, SUN Xueting, DAI Yu, ZHANG Xiaojin, XIA Fan

Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, P. R. China

Received:2024-01-31 Revised:2024-03-01 Online:2024-04-01 Published:2024-03-27
Contact: ZHANG Xiaojin zhangxj@cug.edu.cn;XIA Fan xiafan@cug.edu.cn
Supported by:
This work was supported by the National Natural Science Foundation of China (No. 22090050), the National Key R&D Program of China (No. 2021YFA1200403) and the Joint National Natural Science Foundation of China-Israel Science Foundation (NSFC-ISF) Research Grant Program (No. 22161142020).

摘要/Abstract

摘要： Nanochannels have made great progress and are a promising platform for detecting a series of targets. However, most nanochannels are modified on the inner wall, while ignoring the outer surface. Here, we modified the outer surface of nanochannels with hydrogel. Different from other reported outer-surface modification methods, we directly cover nanochannels with hydrogel to form heterogeneous membrane. The selected hydrogel hardly adsorbs other ions and shows specific adsorption for Cr(VI). The adsorption sites in hydrogel are homogeneous, and Cr(VI) adsorption onto hydrogel is endothermic and spontaneous. The charge in hydrogel changes after Cr(VI) adsorption, and the resulting current changes can be used for the detection of Cr(VI) with the detection limit of 10?11 mol/L. Our platform is expected to be used for Cr(VI) detection in living organisms, especially within cells. This work provides a new approach for outer-surface modification of nanochannels and offers a new choice for nanochannel detection platforms.

关键词: Nanochannel, Hydrogel, Heterogeneous membrane, Cr(VI) detection

Abstract: Nanochannels have made great progress and are a promising platform for detecting a series of targets. However, most nanochannels are modified on the inner wall, while ignoring the outer surface. Here, we modified the outer surface of nanochannels with hydrogel. Different from other reported outer-surface modification methods, we directly cover nanochannels with hydrogel to form heterogeneous membrane. The selected hydrogel hardly adsorbs other ions and shows specific adsorption for Cr(VI). The adsorption sites in hydrogel are homogeneous, and Cr(VI) adsorption onto hydrogel is endothermic and spontaneous. The charge in hydrogel changes after Cr(VI) adsorption, and the resulting current changes can be used for the detection of Cr(VI) with the detection limit of 10?11 mol/L. Our platform is expected to be used for Cr(VI) detection in living organisms, especially within cells. This work provides a new approach for outer-surface modification of nanochannels and offers a new choice for nanochannel detection platforms.

Key words: Nanochannel, Hydrogel, Heterogeneous membrane, Cr(VI) detection

LIU Huan, SUN Xueting, DAI Yu, ZHANG Xiaojin, XIA Fan. Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel[J]. 高等学校化学研究, 2024, 40(2): 326-332.

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Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel

Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel

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