Synthesis of Prebiotic Building Blocks by Photochemistry

doi:10.1007/s40242-020-0289-6

高等学校化学研究 ›› 2020, Vol. 36 ›› Issue (6): 985-991.doi: 10.1007/s40242-020-0289-6

Synthesis of Prebiotic Building Blocks by Photochemistry

LIU Ziwei

MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK

收稿日期:2020-09-18 修回日期:2020-10-13 出版日期:2020-12-01 发布日期:2020-10-15
通讯作者: LIU Ziwei E-mail:zliu@mrc-lmb.cam.ac.uk

Synthesis of Prebiotic Building Blocks by Photochemistry

LIU Ziwei

MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK

Received:2020-09-18 Revised:2020-10-13 Online:2020-12-01 Published:2020-10-15
Contact: LIU Ziwei E-mail:zliu@mrc-lmb.cam.ac.uk

摘要/Abstract

摘要： Ultraviolet(UV) light is a very competent energy source for the synthesis of prebiotic building blocks on early Earth. In aqueous solution, hydrated electron is produced by irradiating ferrocyanide/cuprous cyanide/hydrosulfide by 254 nm UV light. Hydrated electron is a powerful reducing reagent driving the formation of prebiotic building blocks under prebiotically plausible conditions. Here we summarize the photoredox synthesis of prebiotic related building blocks from hydrogen cyanide(HCN) and other prebiotically related molecules. These results indicate biological related building blocks can be generated on the surface of early Earth.

关键词: Prebiotic chemistry, UV irradiation, System chemistry, Origin of life

Abstract: Ultraviolet(UV) light is a very competent energy source for the synthesis of prebiotic building blocks on early Earth. In aqueous solution, hydrated electron is produced by irradiating ferrocyanide/cuprous cyanide/hydrosulfide by 254 nm UV light. Hydrated electron is a powerful reducing reagent driving the formation of prebiotic building blocks under prebiotically plausible conditions. Here we summarize the photoredox synthesis of prebiotic related building blocks from hydrogen cyanide(HCN) and other prebiotically related molecules. These results indicate biological related building blocks can be generated on the surface of early Earth.

Key words: Prebiotic chemistry, UV irradiation, System chemistry, Origin of life

LIU Ziwei. Synthesis of Prebiotic Building Blocks by Photochemistry[J]. 高等学校化学研究, 2020, 36(6): 985-991.

LIU Ziwei. Synthesis of Prebiotic Building Blocks by Photochemistry[J]. Chemical Research in Chinese Universities, 2020, 36(6): 985-991.

参考文献

[1] Rimmer P. B., Xu J., Thompson S. J., Gillen E., Sutherland J. D., Queloz D., Science Advances, 2018, 4, eaar3302
[2] Sasselov D. D., Grotzinger J. P., Sutherland J. D., Science Advances, 2020, 6, eaax3419
[3] Miller S. L., Science, 1953, 117, 528
[4] Oró J., Kimball A. P., Archives of Biochemistry and Biophysics, 1962, 94, 217
[5] Butlerow A., CR Acad. Sci., 1861, 53, 145
[6] Ruiz-Mirazo K., Briones C., de la Escosura A., Chemical Reviews, 2014, 114, 285
[7] Liu Z., Mariani A., Wu L., Ritson D., Folli A., Murphy D., Sutherland J., Chemical Science, 2018, 9, 7053
[8] Xu J., Chmela V., Green N. J., Russell D. A., Janicki M. J., Góra R. W., Szabla R., Bond A. D., Sutherland J. D., Nature, 2020, 582, 60
[9] Liu Z., Wu L. F., Bond A. D., Sutherland J. D., Chemical Communication, 2020, https://doi.org/10.1039/D0CC05752E
[10] Ritson D., Sutherland J. D., Nature Chemistry, 2012, 4, 895
[11] Abou M. N., Ajram G., Rossi J. C., Boiteau L., Duvernay F., Pascal R., Danger G., Chemistry:A European Journal, 2017, 23, 7418
[12] Luther G. W., Theberge S. M., Rozan T. F., Rickard D., Rowlands C. C., Oldroyd A., Environmental Science & Technology, 2002, 36, 394
[13] Wirth T., Über Thioformamid und Kohlenmonosulfid., ETH Zurich, Zurich, 1910
[14] Ritson D. J., Sutherland J. D., Angewandte Chemie International Edition, 2013, 52, 5845
[15] Reynolds J. E., Journal of the Chemical Society, 1869, 22, 1
[16] Lohrmann R., Orgel L. E., Science, 1968, 161, 64
[17] Ritson D. J., Sutherland J. D., Journal of Molecular Evolution, 2014, 78, 245
[18] Strecker A., Justus Liebigs Annalen der Chemie, 1854, 91, 349
[19] Patel B. H., Percivalle C., Ritson D. J., Duffy C. D., Sutherland J. D., Nature Chemistry, 2015, 7, 301
[20] Keefe A. D., Miller S. L., Origins of Life and Evolution of the Biosphere, 1996, 26, 111
[21] Shirom M., Stein G., The Journal of Chemical Physics, 1971, 55, 3372
[22] Marion G. M., Kargel J. S., Crowley J. K. Catling D. C., Icarus, 2013, 225, 342
[23] Halevy I., Zuber M. T., Schrag D. P., Science, 2007, 318, 1903
[24] Kaltenegger L., Sasselov D. D., The Astrophysical Journal, 2010, 708, 1162
[25] Xu J., Ritson D. J., Ranjan S., Todd Z. R., Sasselov D. D., Sutherland J. D., Chemical Communications, 2018, 54, 5566
[26] Powner M. W., Gerland B., Sutherland J. D., Nature, 2009, 459, 239
[27] Steinman G., Lemmon R. M., Calvin M., Science, 1965, 147, 1574
[28] Toner J. D., Catling D. C., Geochimica et Cosmochimica Acta, 2019, 260, 124
[29] Li L., Prywes N., Tam C. P., O'Flaherty D. K., Lelyveld V. S., Izgu E. C., Pal A., Szostak J. W., Journal of the American Chemical Society, 2017, 139, 1810
[30] Walton T., Zhang W., Li L., Tam C. P., Szostak J. W., Angewandte Chemie International Edition, 2019, 131, 10926
[31] Becker S., Thoma I., Deutsch A., Gehrke T., Mayer P., Zipse H., Carell T., Science, 2016, 352, 833
[32] Kim H. J., Kim J., Astrobiology, 2019, 19, 669
[33] Becker S., Feldmann J., Wiedemann S., Okamura H., Schneider C., Iwan K., Crisp A., Rossa M., Amatov T., Carell T., Science, 2019, 366, 76
[34] Hein J. E., Tse E., Blackmond D. G., Nature Chemistry, 2011, 3, 704
[35] Xu J., Tsanakopoulou M., Magnani C. J., Szabla R., Sponer J. E., Sponer J., Gora R. W., Sutherland J. D., Nature Chemistry, 2017, 9, 303
[36] Xu J., Green N. J., Gibard C., Krishnamurthy R., Sutherland J. D., Nature Chemistry, 2019, 11, 457
[37] Liu Z., Rossi J. C., Pascal R., Life, 2019, 9, 26
[38] Pasek M. A., Lauretta D. S., Astrobiology, 2005, 5, 515
[39] Bryant D. E., Kee T. P., Chemcal Communications, 2006, 22, 2344
[40] Gulick A., American Scientist, 1955, 43, 479
[41] Gulick A., Annals of the New York Academy of Sciences, 1957, 69, 309
[42] Ritson D. J., Mojzsis S. J., Sutherland J. D., Nature Geoscience, 2020, 13, 344
[43] Ritson D. J., Xu J., Sutherland J. D., Synlett., 2017, 28, 64

Synthesis of Prebiotic Building Blocks by Photochemistry

Synthesis of Prebiotic Building Blocks by Photochemistry

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics

本文评价