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高等学校化学研究 ›› 2013, Vol. 29 ›› Issue (6): 1214-1218.doi: 10.1007/s40242-013-3092-9

• Articles • 上一篇    下一篇

Silver Chloride Loaded Mesoporous Silica Particles and Their Application in the Antibacterial Coatings on Denture Base

LI Xian-liang1, ZUO Wei-wen2, LUO Meng2, SHI Zuo-sen1, CUI Zhan-chen1, ZHU Song2   

  1. 1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China;
    2. Hospital of Stomatology, Jilin University, Changchun 130021, P. R. China
  • 收稿日期:2013-03-06 修回日期:2013-03-22 出版日期:2013-12-01 发布日期:2013-05-03
  • 通讯作者: LI Xia, ZHU Song E-mail:zhusong1965@163.com
  • 基金资助:

    Supported by the National Natural Science Foundation of China(Nos.81070865, 51173063, 20921003).

Silver Chloride Loaded Mesoporous Silica Particles and Their Application in the Antibacterial Coatings on Denture Base

LI Xian-liang1, ZUO Wei-wen2, LUO Meng2, SHI Zuo-sen1, CUI Zhan-chen1, ZHU Song2   

  1. 1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China;
    2. Hospital of Stomatology, Jilin University, Changchun 130021, P. R. China
  • Received:2013-03-06 Revised:2013-03-22 Online:2013-12-01 Published:2013-05-03
  • Contact: LI Xia, ZHU Song E-mail:zhusong1965@163.com
  • Supported by:

    Supported by the National Natural Science Foundation of China(Nos.81070865, 51173063, 20921003).

摘要:

Thiol-functionalized MCM-41 type mesoporous silica particles(MSPs) were prepared and loaded with silver chloride to act as antibacterial agents. The antibacterial activity of the silver chloride loaded MSPs(AgCl-MSPs) was evaluated by the minimum bactericidal concentration(MBC) against Candida albicans(ATCC 10231). The AgCl-MSPs with the highest antibacterial activity were then dispersed in hybrid coatings with different mass ratios to fabricate antibacterial coatings. The antibacterial activity of the coatings was tested against Candida albicans(ATCC 10231) and Streptococcus mutans(ATCC 25175). The resulting antibacterial coatings exhibited high antibacterial activity, good adhesion to the substrate and high hardness.

关键词: Mesoporous silica, Silver chloride, antibacterial, Coating

Abstract:

Thiol-functionalized MCM-41 type mesoporous silica particles(MSPs) were prepared and loaded with silver chloride to act as antibacterial agents. The antibacterial activity of the silver chloride loaded MSPs(AgCl-MSPs) was evaluated by the minimum bactericidal concentration(MBC) against Candida albicans(ATCC 10231). The AgCl-MSPs with the highest antibacterial activity were then dispersed in hybrid coatings with different mass ratios to fabricate antibacterial coatings. The antibacterial activity of the coatings was tested against Candida albicans(ATCC 10231) and Streptococcus mutans(ATCC 25175). The resulting antibacterial coatings exhibited high antibacterial activity, good adhesion to the substrate and high hardness.

Key words: Mesoporous silica, Silver chloride, antibacterial, Coating