[an error occurred while processing this directive]

高等学校化学研究 ›› 1995, Vol. 11 ›› Issue (3): 189-194.

• Articles • 上一篇    下一篇

Amperometric Glucose Sensor with Tetrathiafulvalene as an Electron Transfer Mediator

SUN Chang-qing, YANG Xu, LUAN Chai-xia, GAO Qian, XU Hong-ding   

  1. Department of Chemistry, Jilin University, Changchun, 130023
  • 收稿日期:1994-11-01 出版日期:1995-08-24 发布日期:2011-08-17

Amperometric Glucose Sensor with Tetrathiafulvalene as an Electron Transfer Mediator

SUN Chang-qing, YANG Xu, LUAN Chai-xia, GAO Qian, XU Hong-ding   

  1. Department of Chemistry, Jilin University, Changchun, 130023
  • Received:1994-11-01 Online:1995-08-24 Published:2011-08-17

PDF (PC)

摘要： A glucose oxidase (GOD) electrode with tetrathiafulvalene(TTF) as an elec-tron transfer mediator is described.By means of Nafion, TTFwas modified on aglassy carbon(GC) electrode surface, and glucose oxidase was then immobilized onthe TTF-Na fion film, forming a GOD-TTF-Na fion enzyme electrode.Characteris-tics of the sensor are shown by cyclic voltammetry and constant potential measure-ments.The sensor responds rapidly to glucose, the time required to reach 95% of the steady-state current is less than 60s.The sensor displays a sensitive catalyticcurrent response to glucose and can be operated in a potential range in which theoxidation of common interfering species, such as ascorbic acid and uric acid, doesnot occur.The sensor is stable for more than 30 days at 4℃ and plasma glucose assays were correlated with spectrophotometry(n=10, r=0.995).

关键词: Tetrathiafulvalene, Nafion, Biosensor, Glucose

Abstract: A glucose oxidase (GOD) electrode with tetrathiafulvalene(TTF) as an elec-tron transfer mediator is described.By means of Nafion, TTFwas modified on aglassy carbon(GC) electrode surface, and glucose oxidase was then immobilized onthe TTF-Na fion film, forming a GOD-TTF-Na fion enzyme electrode.Characteris-tics of the sensor are shown by cyclic voltammetry and constant potential measure-ments.The sensor responds rapidly to glucose, the time required to reach 95% of the steady-state current is less than 60s.The sensor displays a sensitive catalyticcurrent response to glucose and can be operated in a potential range in which theoxidation of common interfering species, such as ascorbic acid and uric acid, doesnot occur.The sensor is stable for more than 30 days at 4℃ and plasma glucose assays were correlated with spectrophotometry(n=10, r=0.995).

Key words: Tetrathiafulvalene, Nafion, Biosensor, Glucose