Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources

doi:10.1007/s40242-015-4341-x

高等学校化学研究 ›› 2015, Vol. 31 ›› Issue (1): 65-70.doi: 10.1007/s40242-015-4341-x

Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources

CHEN Zhanguo, LIU Yali, HU Junli, LIU De'e

Key Laboratory for Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, P. R. China

收稿日期:2014-09-15 修回日期:2014-10-08 出版日期:2015-02-01 发布日期:2014-11-03
通讯作者: CHEN Zhanguo, E-mail:chzhg@snnu.edu.cn E-mail:chzhg@snnu.edu.cn
基金资助:
Supported by the Natural Science Foundation of Shaanxi Province, China(No.2009JM2001), the Innovation Foundation of Pastgraduate Cultivation of Shaanxi Normal University, China(No.2008CXB009) and the Fundamental Research Funds for the Central Universities of China(No.GK261001095).

Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources

CHEN Zhanguo, LIU Yali, HU Junli, LIU De'e

Key Laboratory for Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, P. R. China

Received:2014-09-15 Revised:2014-10-08 Online:2015-02-01 Published:2014-11-03
Contact: CHEN Zhanguo, E-mail:chzhg@snnu.edu.cn E-mail:chzhg@snnu.edu.cn
Supported by:
Supported by the Natural Science Foundation of Shaanxi Province, China(No.2009JM2001), the Innovation Foundation of Pastgraduate Cultivation of Shaanxi Normal University, China(No.2008CXB009) and the Fundamental Research Funds for the Central Universities of China(No.GK261001095).

摘要/Abstract

摘要：

1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) was found to be a new and efficient nitrogen/halogen source for the aminobromination of ethyl α-cyanocinnamate derivatives catalyzed by K₃PO₄. The reaction afforded the aminobrominated products in high yields at room temperature, and the full regiospecificity of all the products were achieved. A possible pathway involving a Michael addition for this aminobromination was suggested.

关键词: Aminobromination, Ethyl α-cyanocinnamate derivative, 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH)

Abstract:

Key words: Aminobromination, Ethyl α-cyanocinnamate derivative, 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH)

CHEN Zhanguo, LIU Yali, HU Junli, LIU De'e. Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources[J]. 高等学校化学研究, 2015, 31(1): 65-70.

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Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources

Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin(DBDMH) as Nitrogen and Halogen Sources

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