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高等学校化学研究 ›› 2013, Vol. 29 ›› Issue (3): 460-465.doi: 10.1007/s40242-013-2487-y

• Articles • 上一篇    下一篇

Synthesis and Fluorescence Properties of Coumarin Glycosides and Triazoylglycosides

WU Zheng1,2, FU Xin-ling3, YANG Nan1, WANG Qiu-an1   

  1. 1. College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China;
    2. School of Pharmaceutical Sciences, Guangxi Medical University, Nanning 530021, P. R. China;
    3. Department of Basic Medical, Changsha Medical University, Changsha 410082, P. R. China
  • 收稿日期:2012-12-07 修回日期:2012-12-27 出版日期:2013-06-01 发布日期:2013-05-15
  • 通讯作者: WANG Qiu-an, E-mail: wangqa@hnu.edu.cn E-mail:wangqa@hnu.edu.cn
  • 基金资助:

    Support by the Personal Training Funds in National Basic Science of China(No.J1103312/J0104) and the Project of Science and Technology of Department of Education of Hunan Province, China(No.10B012).

Synthesis and Fluorescence Properties of Coumarin Glycosides and Triazoylglycosides

WU Zheng1,2, FU Xin-ling3, YANG Nan1, WANG Qiu-an1   

  1. 1. College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China;
    2. School of Pharmaceutical Sciences, Guangxi Medical University, Nanning 530021, P. R. China;
    3. Department of Basic Medical, Changsha Medical University, Changsha 410082, P. R. China
  • Received:2012-12-07 Revised:2012-12-27 Online:2013-06-01 Published:2013-05-15
  • Supported by:

    Support by the Personal Training Funds in National Basic Science of China(No.J1103312/J0104) and the Project of Science and Technology of Department of Education of Hunan Province, China(No.10B012).

被引次数

12

摘要：

Four coumarin glycosides(1―4) and four coumarin triazoylglycosides(5―8) were synthesized by phase transfer catalytic glycosylation and copper-catalyzed azide-alkyne cycloaddition(CuAAC) respectively from 4-methyl-7-hydroxyl coumarin(4-methylumbelliferone). The structures were characterized by 1H NMR, MS or IR. The fluorescent properties of the coumarin glycosides and triazoylglycosides were studied in different solvents and compared to those of 4-methyl-7-hydroxyl coumarin.

关键词: Coumarin glycoside, Coumarin triazolylglycoside, 4-Methyl-7-hydroxyl coumarin, Fluorescence property

Abstract:

Four coumarin glycosides(1―4) and four coumarin triazoylglycosides(5―8) were synthesized by phase transfer catalytic glycosylation and copper-catalyzed azide-alkyne cycloaddition(CuAAC) respectively from 4-methyl-7-hydroxyl coumarin(4-methylumbelliferone). The structures were characterized by 1H NMR, MS or IR. The fluorescent properties of the coumarin glycosides and triazoylglycosides were studied in different solvents and compared to those of 4-methyl-7-hydroxyl coumarin.

Key words: Coumarin glycoside, Coumarin triazolylglycoside, 4-Methyl-7-hydroxyl coumarin, Fluorescence property