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高等学校化学研究 ›› 2006, Vol. 22 ›› Issue (2): 181-184.

• Articles • 上一篇    下一篇

NHS Mediated CdTe Quantum Dots/Albumin Conjugates and Labeling C.Elegans

MA Hui-lian1,2, WANG Chun-lei3, LIU Han-zhi1, LI Wei1, XU Shu-kun2, WANG Li-ping1   

  1. 1. College of Life Science, Jilin University, Changchun 130021, P.R.China;

    2. College of Science, Northeastern University, Shenyang 110004, P.R.China;

    3. Key Lab of Supramolecular Structure and Materials of Educational Ministry, Jilin University, Changchun 130021, P.R.China;
  • 收稿日期:2006-01-10 出版日期:2006-04-24 发布日期:2011-08-06
  • 基金资助:

    Supported by the National Natural Science Foundation of China(No.29774010).

NHS Mediated CdTe Quantum Dots/Albumin Conjugates and Labeling C.Elegans

MA Hui-lian1,2, WANG Chun-lei3, LIU Han-zhi1, LI Wei1, XU Shu-kun2, WANG Li-ping1   

  1. 1. College of Life Science, Jilin University, Changchun 130021, P.R.China;

    2. College of Science, Northeastern University, Shenyang 110004, P.R.China;

    3. Key Lab of Supramolecular Structure and Materials of Educational Ministry, Jilin University, Changchun 130021, P.R.China;
  • Received:2006-01-10 Online:2006-04-24 Published:2011-08-06
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.29774010).

摘要: Luminescent quantum dots(QDs) are a promising alternative to organic dyes for biomedical assays and imaging.A new conjugation method, NHS mediated conjugating, for QDs and BSA was introduced.The QDs-BSA conjugates were confirmed, and their stability has been proved.Caenorhabditis elegans (C.elegans) were used as animal models, and the imaging of QDs in the organism was studied.

关键词: Quantum dots, BSA, Conjugate, C.elegan, Surface encapsulation, Imaging

Abstract: Luminescent quantum dots(QDs) are a promising alternative to organic dyes for biomedical assays and imaging.A new conjugation method, NHS mediated conjugating, for QDs and BSA was introduced.The QDs-BSA conjugates were confirmed, and their stability has been proved.Caenorhabditis elegans (C.elegans) were used as animal models, and the imaging of QDs in the organism was studied.

Key words: Quantum dots, BSA, Conjugate, C.elegan, Surface encapsulation, Imaging