Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones

高等学校化学研究 ›› 1997, Vol. 13 ›› Issue (1): 27-33.

Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones

ZHANG Zi-yi, DONG Heng-shan, GUAN Zuo-wu

National Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000

收稿日期:1996-03-08 出版日期:1997-01-24 发布日期:2011-08-17
基金资助:
Supported by the National Natural Science Foundation of China.

Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones

ZHANG Zi-yi, DONG Heng-shan, GUAN Zuo-wu

National Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000

Received:1996-03-08 Online:1997-01-24 Published:2011-08-17
Supported by:
Supported by the National Natural Science Foundation of China.

摘要/Abstract

摘要： The treatment of 5-amino-1-(4'-chlorophenyl)-1, 2, 3-triazol-4-carbohydrazide with equimolecular aryl isothiocyanate gave new derivatives 1 _a—l . Twelve title compounds were obtained in 42% to 87% yields when compounds 1_a—l were respectively treated with sodium hydroxide aqueous solution(2 mol/L). The products of Dimroth rearrangement were not observed in the experiment. The structures of all the compounds were confirmed by means of IR, ¹H NMR, MS and elementary analysis.

关键词: 1, 2, 3-Triazole, 1, 2, 4-Triazoline-5-thione, Heterocycle, Synthesis

Abstract: The treatment of 5-amino-1-(4'-chlorophenyl)-1, 2, 3-triazol-4-carbohydrazide with equimolecular aryl isothiocyanate gave new derivatives 1 _a—l . Twelve title compounds were obtained in 42% to 87% yields when compounds 1_a—l were respectively treated with sodium hydroxide aqueous solution(2 mol/L). The products of Dimroth rearrangement were not observed in the experiment. The structures of all the compounds were confirmed by means of IR, ¹H NMR, MS and elementary analysis.

Key words: 1,2,3-Triazole, 1,2,4-Triazoline-5-thione, Heterocycle, Synthesis

ZHANG Zi-yi, DONG Heng-shan, GUAN Zuo-wu . Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones[J]. 高等学校化学研究, 1997, 13(1): 27-33.

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Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones

Studies on Thiosemicarbazides and Related Heterocycles(ⅩⅩⅤⅠ) ——Synthesis of 3-[5'-amino-1'-(4" chlorophenyl)-1', 2', 3'-triazol-4 yl]-4-aryl-1, 2, 4-triazoline-5-thiones

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