Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

doi:10.1007/s40242-024-4060-2

高等学校化学研究 ›› 2024, Vol. 40 ›› Issue (5): 776-785.doi: 10.1007/s40242-024-4060-2

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

QI Yi¹, FAN Hailong²

1. Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan;
2. Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo 001-0021, Japan

收稿日期:2024-03-13 出版日期:2024-10-01 发布日期:2024-09-26
通讯作者: FAN Hailong,fanhl@icredd.hokudai.ac.jp E-mail:fanhl@icredd.hokudai.ac.jp
基金资助:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (Nos.JP21K14676,JP24K17728) and the Project of the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) established by the World Premier International Research Initiative (WPI),MEXT,Japan.

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

QI Yi¹, FAN Hailong²

1. Department of Neurosurgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan;
2. Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Sapporo 001-0021, Japan

Received:2024-03-13 Online:2024-10-01 Published:2024-09-26
Contact: FAN Hailong,fanhl@icredd.hokudai.ac.jp E-mail:fanhl@icredd.hokudai.ac.jp
Supported by:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (Nos.JP21K14676,JP24K17728) and the Project of the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) established by the World Premier International Research Initiative (WPI),MEXT,Japan.

摘要/Abstract

摘要： Vascular embolization treatment, a minimally invasive surgery for various blood vessel-related conditions, has emerged as a crucial method in treating such as hemorrhage, arteriovenous malformation, aneurysms, and hypervascular tumors. Liquid embolic agents are gaining prominence due to their distinct advantage in infiltrating distal regions, expanding the scope of embolization beyond the reach of solid agents. Recent strides in biomaterials and technologies have spurred the development of novel liquid embolic agents, addressing challenges posed by traditional options. This mini-review provides a concise overview of the recent progress in water-based liquid embolic agents, highlighting their potential to overcome limitations associated with current embolic materials. By presenting selected research outcomes, we illuminate advancements that enhance the efficacy of liquid embolic agents. Furthermore, the review outlines essential properties for effective liquid embolic agents, offering insights for future developments in this field.

关键词: Endovascular treatment, Liquid embolic agent, Hydrogel

Abstract: Vascular embolization treatment, a minimally invasive surgery for various blood vessel-related conditions, has emerged as a crucial method in treating such as hemorrhage, arteriovenous malformation, aneurysms, and hypervascular tumors. Liquid embolic agents are gaining prominence due to their distinct advantage in infiltrating distal regions, expanding the scope of embolization beyond the reach of solid agents. Recent strides in biomaterials and technologies have spurred the development of novel liquid embolic agents, addressing challenges posed by traditional options. This mini-review provides a concise overview of the recent progress in water-based liquid embolic agents, highlighting their potential to overcome limitations associated with current embolic materials. By presenting selected research outcomes, we illuminate advancements that enhance the efficacy of liquid embolic agents. Furthermore, the review outlines essential properties for effective liquid embolic agents, offering insights for future developments in this field.

Key words: Endovascular treatment, Liquid embolic agent, Hydrogel

QI Yi, FAN Hailong. Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment[J]. 高等学校化学研究, 2024, 40(5): 776-785.

QI Yi, FAN Hailong. Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment[J]. Chemical Research in Chinese Universities, 2024, 40(5): 776-785.

参考文献

[1] Hu J., Albadawi H., Chong B. W., Deipolyi A. R., Sheth R. A., Khademhosseini A., Oklu R., Adv. Mater., 2019, 31, 1901071.
[2] Altman R., Ferreira R., Barragan C., Bhojani N., Lajkosz K., Zorn K. C., Chughtai B., Annamalai G., Elterman D. S., BMC Urol., 2024, 24, 22.
[3] Szmygin P., Szmygin M., Roman T., Jargiełło T., Rola R., Neurol. Neurochir Pol., 2023, 57, 305.
[4] Qi Y., Liu H., Jia J., Li J., Liu A., Jiang C., Clin. Neurol. Neurosurg., 2020, 195, 105882.
[5] Li Z., Di C., Li S., Yang X., Nie G., Acc. Chem. Res., 2019, 52, 2703.
[6] Bruno C. A., Jr., Meyers P. M., Interv. Neurol., 2013, 1, 109.
[7] Schimmel K., Ali M. K., Tan S. Y., Teng J., Do H. M., Steinberg G. K., Stevenson D. A., Spiekerkoetter E., Int. J. Mol. Sci., 2021, 22, 9037.
[8] Pan P., Weinsheimer S., Cooke D., Winkler E., Abla A., Kim H., Su H., J. Cereb. Blood Flow Metab., 2021, 41, 3141.
[9] Qi Y., Sun Y., Wang Y., Jia J., Zhong H., Yang H., Lv M., Liu H., BioMed Res. Int., 2021, 2021, 9976541.
[10] Liu H., Li C., Ren S., Li T., Zhong H., Jia J., Yang H., Qi Y., Feng J., Li Y., Wang Y., Stroke Vasc. Neurol., 2023, doi: 10.1136/svn-2022-002260.
[11] Wang C. Y., Hu J., Sheth R. A., Oklu R., Prog. Biomed. Eng., 2020, 2, 012003.
[12] Leyon J. J., Littlehales T., Rangarajan B., Hoey E. T., Ganeshan A., Curr. Probl. Diagn. Radiol., 2014, 43, 35.
[13] Qi Y., Xu T., Jiang C., Wang Y., Liu H., Neurosurg. Rev., 2022, 45, 1513.
[14] Ko G., Choi J. W., Lee N., Kim D., Hyeon T., Kim H.-C., Biomaterials, 2022, 287, 121634.
[15] Piacentino F., Fontana F., Curti M., Macchi E., Coppola A., Ossola C., Giorgianni A., Marra P., Mosconi C., Ierardi A. M., Basile A., Golfieri R., Carrafiello G., Carcano G., Venturini M., J. Clin. Med., 2021, 10, 4841.
[16] Jiang Y., Zhang Y., Lu Z., Wang X., Bai S., Chen Y., Mao J., Liu G., ChemPhysMater, 2022, 1, 39.
[17] Jin Z. P., Fan H. L., Osanai T., Nonoyama T., Kurokawa T., Hyodoh H., Matoba K., Takeuchi A., Gong J. P., Fujimura M., Proc. Natl. Acad. Sci. USA, 2022, 119, e2206685119.
[18] Fan L., Duan M., Xie Z., Pan K., Wang X., Sun X., Wang Q., Rao W., Liu J., Small, 2020, 16, 1903421.
[19] Poursaid A., Jensen M. M., Huo E., Ghandehari H., J. Controlled Release, 2016, 240, 414.
[20] Lord J., Britton H., Spain S. G., Lewis A. L., J. Mater. Chem. B, 2020, 8, 8207.
[21] Pal A., Blanzy J., Gómez K. J. R., Preul M. C., Vernon B. L., Gels, 2023, 9, 378.
[22] Li X., Ullah M. W., Li B., Chen H., Adv. Healthcare Mater., 2023, 12, 2202787.
[23] Froberg L., Helgstrand F., Clausen C., Steinmetz J., Eckardt H., J. Emerg. Trauma Shock, 2016, 9, 107.
[24] Sasaki K., Okada T., Yamaguchi M., Ahmed M., Gentsu T., Ueshima E., Sofue K., Tanimura K., Yamada H., Sugimoto K., Murakami T., Emerg. Radiol., 2021, 28, 1127.
[25] Eriksson L.-G., Ljungdahl M., Sundbom M., Nyman R., J. Vasc. Interv. Radiol., 2008, 19, 1413.
[26] Fang Y., Han X., Liu L., Lou W., Int. Surg. J., 2018, 51, 223.
[27] Hickman D. A., Pawlowski C. L., Sekhon U. D. S., Marks J., Gupta A. S., Adv. Mater., 2018, 30, 1700859.
[28] Lawton M. T., Rutledge W. C., Kim H., Stapf C., Whitehead K. J., Li D. Y., Krings T., terBrugge K., Kondziolka D., Morgan M. K., Moon K., Spetzler R. F., Nat. Rev. Dis. Primers, 2015, 1, 15008.
[29] Kumar A., Mittal M., Srivastava D., Jaetli V., Chaudhary S., Contemp. Clin. Dent., 2017, 8, 482.
[30] Behravesh S., Yakes W., Gupta N., Naidu S., Chong B. W., Khademhosseini A., Oklu R., Cardiovasc. Diagn. Ther., 2016, 6, 557.
[31] Nassiri N., Cirillo-Penn N. C., Thomas J., J. Vasc. Surg., 2015, 62, 1667.
[32] Zhao B., Fan Y., Xiong Y., Yin R., Zheng K., Li Z., Tan X., Yang H., Zhong M., J. Neurol. Sci., 2016, 371, 62.
[33] Molyneux A. J., Kerr R. S. C., Yu L.-M., Clarke M., Sneade M., Yarnold J. A., Sandercock P., Lancet, 2005, 366, 809.
[34] Loffroy R., Guiu B., Cercueil J.-P., Krause D., Curr. Vasc. Pharmacol., 2009, 7, 250.
[35] Osuga K., Maeda N., Higashihara H., Hori S., Nakazawa T., Tanaka K., Nakamura M., Kishimoto K., Ono Y., Tomiyama N., Int. J. Clin. Oncol., 2012, 17, 306.
[36] Wu B., Zhou J., Ling G., Zhu D., Long Q., World J. Surg. Oncol., 2018, 16, 69.
[37] Dubbelboer I. R., Sjögren E., Lennernäs H., AAPS J., 2018, 20, 96.
[38] Ravina J. H., Ciraru-Vigneron N., Bouret J. M., Herbreteau D., Houdart E., Aymard A., Merland J. J., Lancet, 1995, 346, 671.
[39] Pisco J. M., Bilhim T., Pinheiro L. C., Fernandes L., Pereira J., Costa N. V., Duarte M., Oliveira A. G., J. Vasc. Interv. Radiol., 2016, 27, 1115.
[40] Malling B., Røder M. A., Brasso K., Forman J., Taudorf M., Lönn L., Eur. Radiol., 2019, 29, 287.
[41] Hu X.-E., Shi Y.-R., Zhu X., Tian K.-W., Xu X.-L., J. Drug Delivery Sci. Technol., 2023, 80, 104107.
[42] Lee B. H., West B., McLemore R., Pauken C., Vernon B. L., Biomacromolecules, 2006, 7, 2059.
[43] Shi X., Gao H., Dai F., Feng X., Liu W., Biomater. Sci., 2016, 4, 1673.
[44] Li H., Qian K., Zhang H., Li L., Yan L., Geng S., Zhao H., Zhang H., Xiong B., Li Z., Zheng C., Zhao Y., Yang X., Chem. Eng. J., 2021, 418, 129534.
[45] Li X., Liu W., Ye G., Zhang B., Zhu D., Yao K., Liu Z., Sheng X., Biomaterials, 2005, 26, 7002.
[46] Xie W., Li H., Yu H., Zhou H., Guo A., Yao Q., Zhang L., Zhao Y., Tian H., Li L., Nanoscale, 2023, 15, 1835.
[47] Li L., Cao Y., Zhang H., Zheng M., Xing J., Zheng C., Zhao Y., Yang X., J. Nanobiotechnol., 2023, 21, 413.
[48] Zhou H., Xie W., Guo A., Chen B., Hu S., Zheng M., Yu H., Tian H., Li L., Des. Monomers Polym., 2023, 26, 31.
[49] Zhao H., Zheng C., Feng G., Zhao Y., Liang H., Wu H., Zhou G., Liang B., Wang Y., Xia X., AJNR Am. J. Neuroradiol., 2013, 34, 169.
[50] Zhao Y., Zheng C., Wang Q., Fang J., Zhou G., Zhao H., Yang Y., Xu H., Feng G., Yang X., Adv. Funct. Mater., 2011, 21, 2035.
[51] Li H., Sun H., Liu Y., Yuan B., Hu J., Jiang Y., Li Q., Cao S., Liu H., Xiao B., Shi P., Yang X., Wang S., Zhao Y., Environ. Sci.: Nano, 2023, 10, 3357.
[52] Bearat H. H., Preul M. C., Vernon B. L., J. Biomed. Mater. Res., Part A, 2013, 101A, 2515.
[53] Huang W., Rollett A., Kaplan D. L., Expert Opin. Drug Delivery, 2015, 12, 779.
[54] Cappello J., Crissman J. W., Crissman M., Ferrari F. A., Textor G., Wallis O., Whitledge J. R., Zhou X., Burman D., Aukerman L., Stedronsky E. R., J. Controlled Release, 1998, 53, 105.
[55] Poursaid A., Price R., Tiede A., Olson E., Huo E., McGill L., Ghandehari H., Cappello J., Biomaterials, 2015, 57, 142.
[56] Poursaid A., Jensen M. M., Nourbakhsh I., Weisenberger M., Hellgeth J. W., Sampath S., Cappello J., Ghandehari H., Mol. Pharmaceutics, 2016, 13, 2736.
[57] Dumortier G., Grossiord J. L., Agnely F., Chaumeil J. C., Pharm. Res., 2006, 23, 2709.
[58] Russo E., Villa C., Pharmaceutics, 2019, 11, 671.
[59] Raymond J., Metcalfe A., Salazkin I., Schwarz A., Biomaterials, 2004, 25, 3983.
[60] San Norberto E. M., Taylor J. H., Carrera S., Vaquero C., J. Vasc. Surg., 2012, 56, 1782.
[61] Huang L., Shen M., Li R., Zhang X., Sun Y., Gao P., Fu H., Liu H., He Y., Du Y., Cao J., Duan Y., Oncotarget, 2016, 7, 73280
[62] Yang H., Lei K., Zhou F., Yang X., An Q., Zhu W., Yu L., Ding J., Mater. Sci. Eng. C, 2019, 102, 606.
[63] Kang S. I., Na K., Bae Y. H., Macromol. Symp., 2001, 172, 149.
[64] Han S. K., Na K., Bae Y. H., Colloids Surf. A, 2003, 214, 49.
[65] Shim W. S., Yoo J. S., Bae Y. H., Lee D. S., Biomacromolecules, 2005, 6, 2930.
[66] Lym J. S., Nguyen Q. V., Ahn D. W., Huynh C. T., Jae H. J., Kim Y. I., Lee D. S., Acta Biomater., 2016, 41, 253.
[67] Nguyen Q. V., Lee M. S., Lym J. S., Kim Y. I., Jae H. J., Lee D. S., J. Mater. Chem. B, 2016, 4, 6524.
[68] Nguyen Q. V., Lym J. S., Huynh C. T., Kim B. S., Jae H. J., Kim Y. I., Lee D. S., Polym. Chem., 2016, 7, 5805.
[69] Huynh C. T., Nguyen M. K., Kim J. H., Kang S. W., Kim B. S., Lee D. S., Soft Matter, 2011, 7, 4974.
[70] Huynh C. T., Nguyen Q. V., Lym J. S., Kim B. S., Huynh D. P., Jae H. J., Kim Y. I., Lee D. S., RSC Adv., 2016, 6, 47687.
[71] Lu D., Wang J., Li Y., Zhang Y., Yu L., Xu T., Guo H., Zhang Y., Wang X., Wang X., Teng G., Lei Z., ACS Cent. Sci., 2020, 6, 1977.
[72] Fries F., Tomori T., Schulz-Schaeffer W. J., Jones J., Yilmaz U., Kettner M., Simgen A., Reith W., Mühl-Benninghaus R., J. Neurointerv. Surg., 2022, 14, 286.
[73] Jones J. P., Sima M., O'Hara R. G., Stewart R. J., Adv. Healthcare Mater., 2016, 5, 795.
[74] Avery R. K., Albadawi H., Akbari M., Zhang Y. S., Duggan M. J., Sahani D. V., Olsen B. D., Khademhosseini A., Oklu R., Sci. Transl. Med., 2016, 8, 365ra156.
[75] Smith S. A., Travers R. J., Morrissey J. H., Crit. Rev. Biochem. Mol. Biol., 2015, 50, 326.
[76] Fan H. L., Guo H. L., Wang J. H., Gong J. P., Giant, 2020, 1, 100005.
[77] Israelachvili J. N., Intermolecular and Surface Force, 3rd Edition, Elsevier, Amsterdam, 2010.
[78] Fan H. L., Wang J. H., Tao Z., Huang J. C., Rao P., Kurokawa T., Gong J. P., Nat. Commun., 2019, 10, 5127.
[79] Fan H. L., Cai Y. R., Gong J. P., Sci. China: Chem., 2021, 64, 1560.

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

Recent Progress on Water-based Liquid Embolic Agents in Endovascular Treatment

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