Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

doi:10.1007/s40242-021-0396-z

高等学校化学研究 ›› 2021, Vol. 37 ›› Issue (1): 73-82.doi: 10.1007/s40242-021-0396-z

Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

HOU Yazhen^1,2, JIANG Guoyu², GONG Jianye², SHA Ren¹, WANG Jianguo²

1. College of Chemistry and Environmental Science, Inner Mongolia Normal University, Hohhot 010020, P. R. China;
2. College of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, P. R. China

收稿日期:2020-11-28 修回日期:2020-12-28 出版日期:2021-02-01 发布日期:2021-01-05
通讯作者: SHA Ren, WANG Jianguo E-mail:sr@imnu.edu.cn;wangjg@imu.edu.cn
基金资助:
This work was supported by the National Natural Science Foundation of China(Nos.21871060, 21864020), the Grassland Talent Program of Inner Mongolia Autonomous Region of China, the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Nos.2020JQ02, 2020MS02004) and the Natural Science Foundation of Jiangxi Province of China(No.20192BCBL23013).

Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

HOU Yazhen^1,2, JIANG Guoyu², GONG Jianye², SHA Ren¹, WANG Jianguo²

1. College of Chemistry and Environmental Science, Inner Mongolia Normal University, Hohhot 010020, P. R. China;
2. College of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, P. R. China

Received:2020-11-28 Revised:2020-12-28 Online:2021-02-01 Published:2021-01-05
Contact: SHA Ren, WANG Jianguo E-mail:sr@imnu.edu.cn;wangjg@imu.edu.cn
Supported by:
This work was supported by the National Natural Science Foundation of China(Nos.21871060, 21864020), the Grassland Talent Program of Inner Mongolia Autonomous Region of China, the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Nos.2020JQ02, 2020MS02004) and the Natural Science Foundation of Jiangxi Province of China(No.20192BCBL23013).

摘要/Abstract

摘要： Bioimaging, as a powerful and helpful tool, which allows people to investigate deeply within living organisms, has contributed a lot for both clinical theranostics and scientific research. Pure organic room temperature phosphorescence(RTP) materials with the unique features of ultralong luminescence lifetime and large Stokes shift, can efficiently avoid biological autofluorescence and scattered light through a time-resolved imaging modality, and thus are attracting increasing attention. This review classifies pure organic RTP materials into three categories, including small molecule RTP materials, polymer RTP materials and supramolecular RTP materials, and summarizes the recent advances of pure organic RTP materials for bioimaging applications.

关键词: Bioimaging application, Pure organic room temperature phosphorescence, Phosphorescence lifetime, Time-resolved luminescence imaging, In vivo imaging

Abstract: Bioimaging, as a powerful and helpful tool, which allows people to investigate deeply within living organisms, has contributed a lot for both clinical theranostics and scientific research. Pure organic room temperature phosphorescence(RTP) materials with the unique features of ultralong luminescence lifetime and large Stokes shift, can efficiently avoid biological autofluorescence and scattered light through a time-resolved imaging modality, and thus are attracting increasing attention. This review classifies pure organic RTP materials into three categories, including small molecule RTP materials, polymer RTP materials and supramolecular RTP materials, and summarizes the recent advances of pure organic RTP materials for bioimaging applications.

Key words: Bioimaging application, Pure organic room temperature phosphorescence, Phosphorescence lifetime, Time-resolved luminescence imaging, In vivo imaging

HOU Yazhen, JIANG Guoyu, GONG Jianye, SHA Ren, WANG Jianguo. Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications[J]. 高等学校化学研究, 2021, 37(1): 73-82.

HOU Yazhen, JIANG Guoyu, GONG Jianye, SHA Ren, WANG Jianguo. Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications[J]. Chemical Research in Chinese Universities, 2021, 37(1): 73-82.

参考文献

[1] Kuno S., Akeno H., Ohtani H., Yuasa H., Phys. Chem. Chem. Phys., 2015, 17(24), 15989
[2] Smith B. R., Gambhir S. S., Chem. Rev., 2017, 117(3), 901
[3] Xu S., Chen R. F., Zheng C., Huang W., Adv. Mater., 2016, 28(45), 9920
[4] Hirata S., Totani K., Zhang J. X., Yamashita T., Kaji H., Marder S. R., Watanabe T., Adachi C., Adv. Funct. Mater., 2013, 23(27), 3386
[5] Yang J., Zhen X., Wang B., Gao X., Ren Z., Wang J., Xie Y., Li J., Peng Q., Pu K., Li Z., Nat. Commun., 2018, 9(1), 840
[6] Xu J. J., Takai A., Kobayashi Y., Takeuchi M., Chem. Commun., 2013, 49(76), 8447
[7] You Y. Q., Huang K. W., Liu X. J., Pan X., Zhi J. H., He Q. J., Shi H. F., An Z. F., Ma X., Huang W., Small, 2020, 16(8), 1906733
[8] Ma X., Xu C., Wang J., Tian H., Angew. Chem. Int. Ed., 2018, 57(34), 10854
[9] Tao Y., Chen R., Li H., Yuan J., Wan Y., Jiang H., Chen C., Si Y., Zheng C., Yang B., Xing G., Huang W., Adv. Mater., 2018, 30(44), 1803856
[10] Wang S., Yuan W. Z., Zhang Y., ACS Symp. Ser., 2016, 2, 1
[11] Xiao L., Wu Y. S., Chen J. W., Yu Z. Y., Liu Y. P., Yao J. N., Fu H. B., J. Phys. Chem. A, 2017, 121(45), 8652
[12] Yang X. G., Yan D. P., Chem. Sci., 2016, 7(7), 4519
[13] Yuan W. Z., Shen X. Y., Zhao H., Lam J. W. Y., Tang L., Lu P., Wang C. L., Liu Y., Wang Z. M., Zheng Q., Sun J. Z., Ma Y. G., Tang B. Z., J. Phys. Chem. C, 2010, 114(13), 6091
[14] Zhi J. H., Zhou Q., Shi H. F., An Z. F., Huang W., Chem. Asian. J., 2020, 15(7), 947
[15] Mieno H., Kabe R., Adachi C., Commun. Chem., 2018, 1(27), 1
[16] Zhen X., Tao Y., An Z., Chen P., Xu C., Chen R., Huang W., Pu K., Adv. Mater., 2017, 29(33), 1606665
[17] Fateminia S. M. A., Mao Z., Xu S., Yang Z., Chi Z., Liu B., Angew. Chem. Int. Ed. Engl., 2017, 56(40), 12160
[18] He Z., Gao H., Zhang S., Zheng S., Wang Y., Zhao Z., Ding D., Yang B., Zhang Y., Yuan W. Z., Adv. Mater., 2019, 31(18), 1807222
[19] Zhang T., Gao H., Lv A., Wang Z., Gong Y., Ding D., Ma H., Zhang Y., Yuan W. Z., J. Mater. Chem. C, 2019, 7(29), 9095
[20] Cai S., Shi H., Li J., Gu L., Ni Y., Cheng Z., Wang S., Xiong W. W., Li L., An Z., Huang W., Adv. Mater., 2017, 29(35), 9095
[21] Shi H. F., Zou L., Huang K. W., Wang H., Sun C., Wang S., Ma H. L., He Y. R., Wang J. P., Yu H. D., Yao W., An Z. F., Zhao Q., Huang W., ACS Appl. Mater. Inter., 2019, 11(20), 18103
[22] Wang X. F., Xiao H. Y., Chen P. Z., Yang Q. Z., Chen B., Tung C. H., Chen Y. Z., Wu L. Z., J. Am. Chem. Soc., 2019, 141(12), 5045
[23] Yang J., Gao H., Wang Y., Yu Y., Gong Y., Fang M., Ding D., Hu W., Tang B. Z., Li Z., Mater. Chem. Front., 2019, 3(7), 1391
[24] Nicol A., Kwok R. T. K., Chen C., Zhao W., Chen M., Qu J., Tang B. Z., J. Am. Chem. Soc., 2017, 139(41), 14792
[25] Chen X., Xu C., Wang T., Zhou C., Du J., Wang Z., Xu H., Xie T., Bi G., Jiang J., Zhang X., Demas J. N., Trindle C. O., Luo Y., Zhang G., Angew. Chem. Int. Ed., 2016, 55(34), 9872
[26] Zhang G., Palmer G. M., Dewhirst M. W., Fraser C. L., Nat. Mater., 2009, 8(9), 747
[27] Wang T., Su X. G., Zhang X. P., Huang W. H., Huang L. K., Zhang X. Y., Sun X., Luo Y., Zhang G. Q., J. Mater. Chem. C, 2019, 7(32), 9917
[28] Chen X. H., Liu X. D., Lei J. L., Xu L., Zhao Z. H., Kausar F., Xie X. Y., Zhu X. Y., Zhang Y. M., Yuan W. Z., Mol. Syst. Des. Eng., 2018, 3(2), 364
[29] Zhou Q., Wang Z. Y., Dou X. Y., Wang Y. Z., Liu S. E., Zhang Y. M., Yuan W. Z., Mater. Chem. Front., 2019, 3(2), 257
[30] Ni X. L., Xiao X., Cong H., Zhu Q. J., Xue S. F., Tao Z., Acc. Chem. Res., 2014, 47(4), 1386
[31] Wang H., Ji X., Li Z., Huang F., Adv. Mater., 2017, 29(14), 1606117
[32] Wang J., Huang Z., Ma X., Tian H., Angew. Chem. Int. Ed., 2020, 59(25), 9928
[33] Wang J., Gu X., Ma H., Peng Q., Huang X., Zheng X., Sung S. H. P., Shan G., Lam J. W. Y., Shuai Z., Tang B. Z., Nat. Commun., 2018, 9(1), 2963
[34] Wang J., Gu X., Zhang P., Huang X., Zheng X., Chen M., Feng H., Kwok R. T. K., Lam J. W. Y., Tang B. Z., J. Am. Chem. Soc., 2017, 139(46), 16974

Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

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