Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety

doi:10.1007/s40242-019-9128-z

高等学校化学研究 ›› 2019, Vol. 35 ›› Issue (6): 1008-1011.doi: 10.1007/s40242-019-9128-z

Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety

CAO Yangyang, CAI Zengfei, ZHANG Wenliang, DU Xiaohua

Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, P. R. China

收稿日期:2019-05-07 修回日期:2019-09-06 出版日期:2019-12-01 发布日期:2019-11-29
通讯作者: DU Xiaohua E-mail:duxiaohua@zjut.edu.cn
基金资助:
Supported by the National Key Research & Development Program of China(No.2016YFD0300708).

Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety

CAO Yangyang, CAI Zengfei, ZHANG Wenliang, DU Xiaohua

Catalytic Hydrogenation Research Center, Zhejiang Key Laboratory of Green Pesticides and Cleaner Production Technology, Zhejiang Green Pesticide Collaborative Innovation Center, Zhejiang University of Technology, Hangzhou 310014, P. R. China

Received:2019-05-07 Revised:2019-09-06 Online:2019-12-01 Published:2019-11-29
Contact: DU Xiaohua E-mail:duxiaohua@zjut.edu.cn
Supported by:
Supported by the National Key Research & Development Program of China(No.2016YFD0300708).

摘要/Abstract

摘要： In this paper, a series of new β-methoxyacrylate derivatives containing a substituted phenylpyridine moiety was synthesized and bioassayed. The structures of all compounds were confirmed by nuclear magnetic resonance(NMR) and high-resolution mass spectrometry(HRMS). Preliminary bioassays demonstrated that compound 8d showed more than 95% inhibition against Brassica juncea and Chenopodium serotinum at 37.5 g a.i./10⁴ m², when compared with the positive control halauxifen-methyl at 150 g a.i./10⁴ m². The present work demonstrated that compound 8d exhibited the more promising herbicidal activity and may serve as a new herbicidal agent for herbicide.

关键词: β-Methoxyacrylate, Phenylpyridine, Herbicidal activity

Abstract: In this paper, a series of new β-methoxyacrylate derivatives containing a substituted phenylpyridine moiety was synthesized and bioassayed. The structures of all compounds were confirmed by nuclear magnetic resonance(NMR) and high-resolution mass spectrometry(HRMS). Preliminary bioassays demonstrated that compound 8d showed more than 95% inhibition against Brassica juncea and Chenopodium serotinum at 37.5 g a.i./10⁴ m², when compared with the positive control halauxifen-methyl at 150 g a.i./10⁴ m². The present work demonstrated that compound 8d exhibited the more promising herbicidal activity and may serve as a new herbicidal agent for herbicide.

Key words: β-Methoxyacrylate, Phenylpyridine, Herbicidal activity

CAO Yangyang, CAI Zengfei, ZHANG Wenliang, DU Xiaohua. Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety[J]. 高等学校化学研究, 2019, 35(6): 1008-1011.

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Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety

Synthesis and Herbicidal Activity of Novel β-Methoxyacrylate Derivatives Containing a Substituted Phenylpyridine Moiety

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