Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole

doi:10.1007/s40242-013-2167-y

高等学校化学研究 ›› 2013, Vol. 29 ›› Issue (1): 51-56.doi: 10.1007/s40242-013-2167-y

Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole

ZHAO Yu, LI Yong-qiang, XIONG Li-xia, XU Li-ping, PENG Li-na, LI Fang, LI Zheng-ming

National Pesticidal Engineering Centre(Tianjin), State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, P. R. China

收稿日期:2012-04-26 修回日期:2012-06-15 出版日期:2013-02-01 发布日期:2013-01-23
基金资助:
Supported by the Fundamental Research Funds for the Central Universities and the Specialized Research Fund for the Doctoral Program of Higher Education(No.20110031120011).

Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole

ZHAO Yu, LI Yong-qiang, XIONG Li-xia, XU Li-ping, PENG Li-na, LI Fang, LI Zheng-ming

National Pesticidal Engineering Centre(Tianjin), State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, P. R. China

Received:2012-04-26 Revised:2012-06-15 Online:2013-02-01 Published:2013-01-23
Supported by:
Supported by the Fundamental Research Funds for the Central Universities and the Specialized Research Fund for the Doctoral Program of Higher Education(No.20110031120011).

摘要/Abstract

摘要：

In search of environmentally benign insecticides with high activity, low toxicity and low residue, a series of novel anthranilic diamide derivatives containing N-pyridylpyrazole was designed and synthesized. All the compounds were characterized by ¹H NMR spectroscopy and elemental analysis. The single crystal structure of compound 8j was determined by X-ray diffraction. The insecticidal activities of the new compounds were evaluated. The results show that some compounds exhibited moderate insecticidal activities against Lepidoptera pests. Among this series of compounds, compounds 8o and 8p showed 100% larvicidal activity against Mythimna separate Walker, Plutella xylostella Linnaeus and Laphygma exigua Hubner at a test concentration of 200 mg/kg, which is equal to the commercial chlorantraniliprole.

关键词: Anthranilic diamide, Ryanodine receptor, Insecticidal activity

Abstract:

Key words: Anthranilic diamide, Ryanodine receptor, Insecticidal activity

ZHAO Yu, LI Yong-qiang, XIONG Li-xia, XU Li-ping, PENG Li-na, LI Fang, LI Zheng-ming. Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole[J]. 高等学校化学研究, 2013, 29(1): 51-56.

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Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole

Design, Syntheses and Biological Activities of Novel Anthranilic Diamide Insecticides Containing N-Pyridylpyrazole

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