Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)

高等学校化学研究 ›› 2010, Vol. 26 ›› Issue (1): 161-164.

• Research Note • 上一篇

Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)

ZHANG Xing, WU Jiao, HAN Zhuang, MEI Wen-li* and DAI Hao-fu*

Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P. R. China

收稿日期:2008-12-23 修回日期:2009-01-13 出版日期:2010-01-04 发布日期:2010-03-29
通讯作者: DAI Hao-fu. E-mail: hfdai@yahoo.cn; MEI Wen-li. E-mail: meiwenli@yahoo.com.cn
基金资助:
Supported by the National Programs for Science and Technology Development of China(No.2007B127B04).

Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)

ZHANG Xing, WU Jiao, HAN Zhuang, MEI Wen-li* and DAI Hao-fu*

Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P. R. China

Received:2008-12-23 Revised:2009-01-13 Online:2010-01-04 Published:2010-03-29
Contact: DAI Hao-fu. E-mail: hfdai@yahoo.cn; MEI Wen-li. E-mail: meiwenli@yahoo.com.cn
Supported by:
Supported by the National Programs for Science and Technology Development of China(No.2007B127B04).

摘要/Abstract

摘要：

Areca nut, the ripe fruit of the tree Areca catechu is ascribed a number of medicinal properties. The EtOAc extract of areca nut exhibited considerable antioxidant in the 1,1-diphenyl-2-picrydrazyl (DPPH) radical-scavenging assay. Bioassay-guided purification of the extract led to the isolation of 11 phenolic compounds, whose structures were determined by detailed spectroscopic analysis, including UV, IR, MS, 1D, 2D and ROESY NMR techniques. Of them, compound 1 was a new phenylpropanoid, compounds 1–9 and 11 were isolated from genus of Areca for the first time. All these compounds were examined for their antioxidant activities by the DPPH method, and the results showed that these compounds contributed to the antioxidant activity of areca nut. Compound 11 exhibited significant cytotoxic activity after examining all these compounds by using MTT assay.

关键词: Areca catechu; Phenylpropanoid; DPPH; Antioxidant activity; Cytotoxic activity

Abstract:

Key words: Areca catechu; Phenylpropanoid; DPPH; Antioxidant activity; Cytotoxic activity

ZHANG Xing, WU Jiao, HAN Zhuang, MEI Wen-li* and DAI Hao-fu*. Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)[J]. 高等学校化学研究, 2010, 26(1): 161-164.

ZHANG Xing, WU Jiao, HAN Zhuang, MEI Wen-li* and DAI Hao-fu*. Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)[J]. Chemical Research in Chinese Universities, 2010, 26(1): 161-164.

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Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)

Antioxidant and Cytotoxic Phenolic Compounds of Areca Nut(Areca catechu)

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