高等学校化学研究 ›› 2016, Vol. 32 ›› Issue (2): 207-211.doi: 10.1007/s40242-016-5350-0
Synthesis and Bioactivity of a Novel Bismuthoxide Schiff-base Complex Derived from Salen-like Ligand and Bismuth(Ⅲ) Nitrate
LI Chuanhua1, JIANG Jianhong1, LI Xu1, XIAO Shengxiong1, WEI Deliang1, JIANG Chao1, XIE Jinqi1, PENG Mengna1, GU Huiwen2, LI Qiangguo1
- 1. Hunan Provincial Key Laboratory of Xiangnan Rare-precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, P. R. China;
2. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
Synthesis and Bioactivity of a Novel Bismuthoxide Schiff-base Complex Derived from Salen-like Ligand and Bismuth(Ⅲ) Nitrate
LI Chuanhua1, JIANG Jianhong1, LI Xu1, XIAO Shengxiong1, WEI Deliang1, JIANG Chao1, XIE Jinqi1, PENG Mengna1, GU Huiwen2, LI Qiangguo1
- 1. Hunan Provincial Key Laboratory of Xiangnan Rare-precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, P. R. China;
2. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
摘要：
In this paper, a novel bismuthoxide Schiff-base complex [Bi9O8(vanen)3(NO3)2(CH3OH)2(H2O)·3NO3·5.5H2O](abbreviated as Bivanen) was synthesized with Salen-like ligand H2vanen[H2vanen=N,N'-ethylene bis(3-methoxysalicylideneimine)] and bismuth(Ⅲ) nitrate. Its structure was characterized by IR spectra, NMR spectra and X-ray diffraction. In particular, the biology activities of the ligand and the complex against Schizosaccharomyces pombe(S. pombe) were studied using biological microcalorimetry. The metabolic thermogenic curves of S. pombe were measured at 32.00℃. Then, some quantitative thermokinetic parameters of growth metabolism of S. pombe including the rate constant(k), inhibition ratio(I) and half inhibition concentration(IC50) were calculated. Experimental results showed that the k values of S. pombe decreased while I values of S. pombe increased with the increase of concentrations of the ligand and the complex. The IC50 of the ligand and the complex were found to be 0.067 and 0.037 mmol/L, respectively.