[an error occurred while processing this directive]

高等学校化学研究 ›› 2011, Vol. 27 ›› Issue (6): 977-980.

• Articles • 上一篇    下一篇

Synthesis of 2-Phenyl-10-substituted Hymenialdisine Derivatives

WU Yi, WANG Yu, QIN Yong and SONG Hao*   

  1. Department of Chemistry of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China
  • 收稿日期:2010-12-09 修回日期:2011-09-02 出版日期:2011-11-25 发布日期:2011-11-07
  • 通讯作者: SONG Hao E-mail:songhao@scu.edu.cn
  • 基金资助:

    Supported by the National Natural Science Foundation of China(No.21002066) and the Scientific Research Foundation for Young Teachers of Sichuan University, China(No.2009SCU11181).

Synthesis of 2-Phenyl-10-substituted Hymenialdisine Derivatives

WU Yi, WANG Yu, QIN Yong and SONG Hao*   

  1. Department of Chemistry of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China
  • Received:2010-12-09 Revised:2011-09-02 Online:2011-11-25 Published:2011-11-07
  • Contact: SONG Hao E-mail:songhao@scu.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.21002066) and the Scientific Research Foundation for Young Teachers of Sichuan University, China(No.2009SCU11181).

PDF (PC)

被引次数

4

摘要： A series of novel 2-phenyl-10-substituted hymenialdisine derivatives was synthesized via the microwave-assisted Suzuki-Miyaura cross-coupling reactions of the 2-phenyl derivative of hymenialdisine and boronic acid, which enabled the successful introduction of electron-donating and electron-withdrawing groups to the 2-phenyl- hymenialdisine derivatives in good yields.

关键词: Hymenialdisine, Suzuki-Miyaura reaction, 2-Phenyl-10-substituted hymenialdisine derivative

Abstract: A series of novel 2-phenyl-10-substituted hymenialdisine derivatives was synthesized via the microwave-assisted Suzuki-Miyaura cross-coupling reactions of the 2-phenyl derivative of hymenialdisine and boronic acid, which enabled the successful introduction of electron-donating and electron-withdrawing groups to the 2-phenyl- hymenialdisine derivatives in good yields.

Key words: Hymenialdisine, Suzuki-Miyaura reaction, 2-Phenyl-10-substituted hymenialdisine derivative